Dr Rima Shah

 Pharmacology

Dr. Rima Shah

Associate Professor

MBBS; MD (Pharmacology)

     

     

    1. PATENT:

    Granted a “PATENT” for a new liquid pharmaceutical formulation of the drug “NINTEDANIB” by THE PATENT OFFICE, GOVT of INDIA in October 2022 for 20 years. Nintedanib is a small molecule kinase inhibitor used in the treatment of pulmonary fibrosis, systemic sclerosis-associated interstitial lung disease, and non-small cell lung cancer.

     

    1. BOOKS PUBLISHED:

    A book entitled “Standard Treatment Guidelines for family physicians” has been published – in collaboration with association of family physicians of India (AFPI) and distributed to all family physicians in a national conference of AFPI for better patient care (2013)

    1. LIST OF PUBLICATION:

     

    1. Singhal S, Shah RB, Bansal S, Dutta S. Doctor–patient communication practices: A cross-sectional survey on Indian physicians. Journal of Family Medicine and Primary Care. 2024 Nov 1;13(11):5198-206.
    2. Singhal S, Dutta SB, Bansal S, Dutta S, Shah RB. Zinc as An Emerging Therapy in the Management of Migraine: A Systematic Review. Neurol India. 2024 Sep 1;72(5):934-942. doi: 10.4103/neurol-india.Neurol-India-D-23-00337. Epub 2024 Oct 19. PMID: 39428763.
    3. Dutta S, Shah RB, Singhal S, Dutta SB, Bansal S, Sinha S, Haque M. Metformin's Enigma: Bridging Gaps in Research on Potential Benefits & Associated Risks - A Critical Plea for Comprehensive Investigation [Response to Letter]. Drug Des Devel Ther. 2024 Sep 7;18:4029-4031. doi: 10.2147/DDDT.S491638. PMID: 39268391; PMCID: PMC11390828.
    4. Piparva KG, Dutta S, Singhal S, Shah R. A critical evaluation of contents, labelling, and cost of hand sanitizers marketed in India during COVID-19 pandemic. J Family Med Prim Care. 2024 Jun;13(6):2289-2294. doi: 10.4103/jfmpc.jfmpc_943_23. Epub 2024 Jun 14. PMID: 39027847; PMCID: PMC11254054.
    5. Dutta S, Singhal S, Shah R. A Systematic Analysis of COVID-19 Clinical Trials Registered in the Clinical Trials Registry of India. Cureus. 2024 Apr 9;16(4):e57939. doi: 10.7759/cureus.57939. PMID: 38738059; PMCID: PMC11082480.
    6. Modi B, Sharma M, Hemani H, Joshi H, Kumar P, Narayanan S, Shah R. Analysis of Vocal Signatures of COVID-19 in Cough Sounds: A Newer Diagnostic Approach Using Artificial Intelligence. Cureus. 2024 Mar 18;16(3):e56412. doi: 10.7759/cureus.56412. PMID: 38638791; PMCID: PMC11024064.
    7. Dutta S, Shah R, Singhal S, Singh S, Piparva K, Katoch CDS. A systematic review and meta-analysis of tolerability, cardiac safety and efficacy of inclisiran for the therapy of hyperlipidemic patients. Expert Opin Drug Saf. 2024 Feb;23(2):187-198. doi: 10.1080/14740338.2023.2293201. Epub 2023 Dec 19. PMID: 38063346.
    8. Dutta S, Singhal S, Shah R, Charan J, Dhingra S, Haque M. Daridorexant as a novel pharmacotherapeutic approach in insomnia: a systematic review and meta-analysis. Expert Opin Drug Saf. 2023 Jul-Dec;22(12):1237-1251. doi: 10.1080/14740338.2023.2243217. Epub 2023 Aug 7. PMID: 37526060.
    9. Singhal S, Shah RB, Piparva KG, Dutta S. Are we providing complete drug information to its users? Status of information adequacy of package insert in India. J Family Med Prim Care. 2023 Jul;12(7):1399-1405. doi: 10.4103/jfmpc.jfmpc_1883_22. Epub 2023 Jul 14. PMID: 37649754; PMCID: PMC10465050.
    10. Dutta S, Shah RB, Singhal S, Dutta SB, Bansal S, Sinha S, Haque M. Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes. Drug Des Devel Ther. 2023 Jun 26;17:1907-1932. doi: 10.2147/DDDT.S409373. PMID: 37397787; PMCID: PMC10312383.
    11. Shah R, Khakhkhar T, Modi B. Efficacy and Safety of Different Drug Regimens for Tuberculosis Preventive Treatment: A Systematic Review and Meta-Analysis. Cureus. 2023 Apr 26;15(4):e38182. doi: 10.7759/cureus.38182. PMID: 37252497; PMCID: PMC10224701.
    12. Singh RD, Avadhesh A, Sharma G, Dholariya S, Shah RB, Goyal B, Gupta SC. Potential of Cytochrome P450, a Family of Xenobiotic Metabolizing Enzymes, in Cancer Therapy. Antioxid Redox Signal. 2023 Apr;38(10-12):853-876. doi: 10.1089/ars.2022.0116. Epub 2023 Mar 27. PMID: 36242099.
    13. Singhal S, Dutta S, Thakker Z, Shah R. Indian Essential Medicine List for Children: Time to Revisit. Cureus. 2023 Feb 22;15(2):e35340. doi: 10.7759/cureus.35340. PMID: 36974248; PMCID: PMC10039369.
    14. Shah R, Shah H, Thakkar K, Parikh N. Conventional Therapies of Oral Cancers: Highlights on Chemotherapeutic Agents and Radiotherapy, Their Adverse Effects, and the Cost Burden of Conventional Therapies. Crit Rev Oncog. 2023;28(2):1-10. doi: 10.1615/CritRevOncog.2023046835. PMID: 37830213.
    15. Shah R, Kadeval A, Shah D, Shah J. Mountain sickness-pathophysiological and pharmacological aspects. Int J Basic Appl Physiol. 2023;12(1):11-16.
    16. Dutta S, Singhal S, Shah RB, Haque M. Immunotherapy and Targeted Therapy in the Management of Oral Cancers. Crit Rev Oncog. 2022;27(4):23-37. doi: 10.1615/CritRevOncog.2022046361. PMID: 37199300.
    17. Sanghani H, Bansal S, Parmar V, Shah R. Study of Arterial Blood Gas Analysis in Moderate-to-Severe COVID-19 Patients. Cureus. 2022 Jul 10;14(7):e26715. doi: 10.7759/cureus.26715. PMID: 35967170; PMCID: PMC9362693.
    18. Agarwal A, Shah RB. 3D Printing Healthcare Technology and its Role in COVID-19 Pandemic Management. Journal of Association for Medical Updates 2022; 2(1):1-7.
    19. Prajapati HS, Thacker V, Shah R, Chaudhari V, Patel S, Shah M, Patel P, Gohil T, Chaturvedi N, Shah K. Drug utilization study in ophthalmology outpatient department of a tertiary care teaching hospital. Natl J Physiol Pharm Pharmacol 2022;12(3):391-4.
    20. Desai H, Shah R, Shah H, Thakkar K. Prevalence and medicinal practices for osteoarthritis in western India. Natl J Physiol Pharm Pharmacol. 2021; 11(1): 78-83.
    21. Shah H, Shah R, Sanghani H, Lakhani N. Health related quality of life (HRQoL) and its associated surgical factors in diabetes foot ulcer patients. J Clin Invest Surg. 2020; 5(2): 83-90
    22. Shah RB, Patel S, Chaudhary V.  Comparison of effects of amitriptyline and venlafaxine on cognitive and psychomotor functions in healthy volunteers: A randomized parallel group study. Natl J Physiol Pharm Pharmacol. 2020; 10(10): 927-935.
    23. Thakur M, Shah R, Dave DJ, Buch JG. Analysis of Prescribing Patterns in Paediatric Respiratory Tract Infections with the Focus on Antimicrobial Use, Adverse Effects and Cost Of Drug Therapy. J Pharm Pharmacol Res 2020; 4 (1): 001-014
    24. Shah RB, Shah AM, Pate PM, Thakker RM. Stigma associated with tuberculosis–An Indian perspective. Natl J Physiol Pharm Pharmacol  2020;10(07):579-585.
    25. Shah RB, Patel JM, Shah AM, Desai GJ, Buch JG. determinants of health-related quality of life in patients with hypertension. Natl J Physiol Pharm Pharmacol  2020;10(03):262-269.
    26. Manjariya JB, Shah R, Miruliya AM. Evaluation of Fever Management Practices in Rural India. Int J Clin Pharmacol Toxicol. 2020;9(1):323-330
    27. Dhanani J, Dihora R, Goti A, Shah R. Assessment of parents’ understanding of pediatric medical prescriptions. Pediatric Rev Int J Pediatr Res. 2020;7(6):271-278.
    28. Patel SP, Shah RB. Study of effect of propranolol, atenolol and celiprolol on exercise induced changes in heart rate, blood pressure and peak expiratory flow rate in healthy human volunteers. Int J Basic Clin Pharmacol 2019;8(5):950-5.
    29. Shah AM, Shah RB, Kachoria S. Health-related quality of life and associated factors in patients with chronic obstructive pulmonary disease. Drugs Ther Perspect. 2019;35(5):241-9.
    30. Shah G, Shah RB, Shah D. Analysis of Diflunisal in dental formulation. Global Trends Pharm Sci, 2018; 9(1): 5005 - 5011
    31. Rathod D, Pandya P, Pandya I, Shah G, Shah R, Padhiyar B. Comparison of efficacy of commercially available vs. freshly prepared salicylic acid peel in treatment of acne: a randomized open-label study. Biomed Dermatol. 2018;2(1):1-8. doi:  https://doi.org/10.1186/s41702-018-0036-5
    32. Shah AM, Shah RB, Dave PN. Factors contributing to development of multidrug-resistant tuberculosis. Natl J Physiol Pharm Pharmacol 2018;8(10):1463-1469.
    33. Pandya I, Pandya P, Pethani N, Shah RB. Comparative evaluation of adverse drug reactions in patients of acne prescribed with either topical benzyl peroxide or retinoic acid in a tertiary care teaching hospital. International Journal of Research. 2017 Apr;3(2):228.
    34. Chaudhari VP, Patel J, Shah R, Shah A. Pharmacoepidemiological profile and appropriateness of drug use in paediatric diarrhoea patients: a cross sectional study in western India. Int J Basic Clin Pharmacol 2017;6:2062-9.
    35. Khakhkhar T, Shah R, Hemavathi KG. Current status of post-operative antibiotic prophylaxis in surgical wards. Natl J Physiol Pharm Pharmacol.2016;6(6):622-6.
    36. Patel SR, Shah AM, Shah RB, Buch JG. Evaluation of drug utilization pattern of antimicrobials using ATC/ DDD system in intensive care unit of a tertiary-care teaching hospital. Int J Med Sci Public Health 2016;5:80-84
    37. Khakhkhar T, Shah R, Hemavathi KG. Relationship between timing of surgical antimicrobial prophylaxis and surgical site infection in a tertiary-care hospital. Drugs Ther Perspect. 2016;32(12):539-44.
    38. Shah RB, Patel M, Maahs DM, Shah VN. Insulin delivery methods: Past, present and future. Int J Pharm Investig.2016;6(1):1-9.  . doi: 10.4103/2230-973X.176456. PMID: 27014614; PMCID: PMC4787057.
    39. Shah RB, Patel M, Maahs DM, Shah VN. Insulin delivery methods: Past, present and future. Int J Pharm Investig. 2016 Jan-Mar;6(1):1-9. doi: 10.4103/2230-973X.176456. PMID: 27014614; PMCID: PMC4787057.
    40. Patel HN, Shah RB, Gajjar BM. Evaluation of the role of zinc supplementation in treatment of diarrhoea in paediatric patients: a randomized open-label study. Drugs Ther Perspect  2015;31 (1), 34–38.
    41. Dudhia S, Shah RB, Agrawal P, Shah A, Date S. Efficacy and safety of clindamycin gel plus either benzoyl peroxide gel or adapalene gel in the treatment of acne: a randomized open-label study. Drugs Ther Perspect. 2015;31(6):208-12.
    42. Patel S, Shah RB, Desai SV. A study of prevailing scenario of Fixed- Dose- Combinations (FDCs) available in Indian market. Int J Pharm 2015; 5(4): 1155-1163
    43. Patel NS, Shah RB, Buch JG. Drug utilization pattern of NSAIDs assessed with the anatomical therapeutic chemical classification/defined daily dose system in an orthopedic department. Drugs Ther Perspect.  2015;31(10):358-64.
    44. Vaidya KS, Modi NB, Shah RB, Datte SK. Evaluation of Analgesic Activity of Herbal Formulation Triphala and Comparison with That of Paracetamol in Mice. Research and reviews: Journal of pharmacology and toxicological studies 2014; 2 (1):15-20
    45. Modi N, Vaidya K, Dudhia S, Shah R, et al. A study of adverse drug reactions to radio contrast media in a tertiary care teaching rural hospital. Int J Med Sci Public Health. 2014;3(2):133–6.
    46. Thakker RM, Mundhra S, Upadhyay G, Shah RB, Shah AM. Chronic cor-pulmonale: The experience of a tertiary care teaching hospital in Gujarat. Int J Med Sci Public Health 2014;3:1169-1172.
    47. Mehta M, Shah J, Khakhkhar T, Shah RB, Hemavathi KG. Anticonvulsant hypersensitivity syndrome associated with carbamazepine administration: Case series. J Pharmacol Pharmacother. 2014; 5(1):59-62
    48. Mehta M, Shah J, Khakhkhar T, Shah R, Hemavathi KG. Anticonvulsant hypersensitivity syndrome associated with carbamazepine administration: Case series. J Pharmacol Pharmacother. 2014 Jan;5(1):59-62. doi: 10.4103/0976-500X.124428. PMID: 24554914; PMCID: PMC3917170.
    49. Shah  RB, Desai SV, Gajjar BM. Factors responsible for noncompliance to drug therapy in the elderly and the impact of patient education on improving compliance. Drugs Ther Perspect 2013; 29 (11), 360–366
    50. Shah AM, Shah RB. Trends of articles published in National Journal of Physiology, Pharmacy and Pharmacology (NJPPP). Natl J Physiol Pharm Pharmacol. 2013;3(2):111-7.
    51. Shah AM, Shah RB, Gajjar BM. Cost burden of inappropriate peri-operative antibacterial use in a teaching tertiary-care rural hospital in India. Drugs Ther Perspect. 2013;29(8):247-52.
    52. Khakhkhar T, Mehta M, Shah R, Sharma D. Evaluation of drug promotional literatures using WHO guidelines. J Pharm Negative Results. 2013;4(1):33-8
    53. Desai P, Patel S, Shah R, Desai S. A comprehensive evaluation of rationality of cough and cold medicines available in Indian market. Journal of the Indian Medical Association. 2013 Feb 1;111(2):94-8.
    54. Patel S, Desai P, Shah RB, Desai SV. Prescribing pattern of cough and cold medicines in central Gujarat. International Journal of Medical Science and Public Health. 2013 ; 2(2): 196-203.
    55. Shah J, Khakhkhar T, Bhirud S, Shah RB, Date S. Study of utilization pattern of anti-hypertensive drugs in hypertensive diabetic patients with or without reduced renal function at tertiary care teaching hospital. Int J Med Sci Public Health 2013;2(2):175-80.
    56. Vijayendra A, Modi N, Vaidya K, Shah RB, Desai SV. Phenytoin induced toxic epidermal necrolysis: A case report. Int J Med Sci Public Health 2013; 2(2):483-486
    57. Shah RB, Shah SP, Shah RS. Steroid induced central serous chorioretinopathy – A Review. Opthalmology international. 2013; summer:58-61
    58. Shah RB, Gajjar BM, Desai SV. A profile of adverse drug reactions with risk factors among geriatric patients in a tertiary care teaching rural hospital in India. Natl J Physiol Pharm Pharmacol. 2012; 2(2): 113-122. doi:10.5455/njppp.2012.2.113-122.
    59. Shah RB, Gajjar BM, Desai SV. Drug utilization pattern among geriatric patients assessed with the anatomical therapeutic chemical classification / defined daily dose system in a rural tertiary care teaching hospital. Int J Nutr Pharmacol Neurol Dis 2012;2:258-65
    60. Tripathi S, Shah R, Sharma DC. Analgesic activity of fixed dose combinations of paracetamol with diclofenac sodium and paracetamol with tramadol on different pain models in healthy volunteers - A randomized double blind crossover study. J Anaesthesiol Clin Pharmacol. 2012 Oct;28(4):465-9. doi: 10.4103/0970-9185.101912. PMID: 23225925; PMCID: PMC3511942.
    61. Shah RB, Gajjar BM, Desai SV. Evaluation of the appropriateness of prescribing in geriatric patients using Beers criteria and Phadke's criteria and comparison thereof. J Pharmacol Pharmacother. 2011 Oct;2(4):248-52. doi: 10.4103/0976-500X.85948. PMID: 22025852; PMCID: PMC3198519.
    62. Shah AM, Dhanani JV, Shah RB. Evaluation of prescription pattern in terms of essentiality and rationality and assessment of Hospital pharmacy services utilization in tertiary care teaching hospital. Indian J Pharm Pract 2010; 3(2): 11-15.

     

    1. AWARDS/HONORS RECEIVED:

     

    • Awarded first prize in oral presentation at I was awarded with a “Best paper award” in faculty category for my oral presentation at the SoPICON 2025 organized at AIIMS Bhopal, Feb 2025
    • Awarded with a highest honour as “National Therapeutic Research Award” for being the first academic pharmacologist to develop a drug formulation and obtained a “PATENT” for it at NAPTICON 2024 organized at AIIMS Nagpur.
    • As a Judge in poster competition at NAPTICON 2024 at AIIMS Nagpur
    • Awarded First prize in oral paper presentation at National Conference: “All India medical undergraduate conference – Nexus 2019”
    • Awarded with token of appreciation (Shield) for taking guest lecture on “ICH-GCP Guidelines” as training program at GMERS Medical College, Patan
    • Awarded with token of appreciation (Shield) for taking guest lecture on “ICH-GCP Guidelines” as training program at GMERS Medical College, Himmatnagar
    • Awarded with token of appreciation (Shield) for taking guest lecture on “ICH-GCP Guidelines” as training program at American Institute of Medical Sciences, Udaipur, Rajasthan
    • As a chairperson in workshop – “Basic skills for medical undergraduates” in a national conference and received a shield/momento for the same.
    • My research projects got selected for 3 consecutive years at ICMR – Short Term Studentship Program and through students got scholarship for the same (2015-17)
    • Delivered a guest lecture on: “Reference writing” in a pre-conference workshop on scientific writing at National conference of Indian Pharmacological Society, 2015. (IPS - India)
    • Delivered lecture on “Ethics and ICH – GCP Guidelines” at AIIMS, Rajkot on 27-28th January, 2022.

     

    1. AREA OF INTEREST:

    Pharmacotherapeutics, Clinical Pharmacology, Rational use of Medicines, Pharmacovigilance & Materiovigilance, Drug development

     

    1. MEMBERSHIP OF PROFESSIONAL/ACADEMIC/RESEARCH BODIES:
    1. Member of Indian Medical Association (IMA)
    2. Member of Gujarat Medical Association (GMA)
    3. Member of Indian Pharmacology Society (IPS)
    4. Member of Indian society for rational pharmacotherapeutics (ISRPT)
    5. Member of National Medicos organization (NMO)
    6. Association of Physiologist and Pharmacologist of India (APPI)
    7. Member of National Association of Pharmacology and therapeutics (NPT)

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